Address:School of Mathematical Sciences, University Park, University of Nottingham,

Nottingham, NG7 2RD, United Kingdom.

Email:Web:http://www.maths.nottingham.ac.uk/~tk/

Phone:+44 (0)115 95 14922 (Work)Mobile:+44 (0)7804 227889

Date of Birth:2nd February 1980Nationality:Greek

- 08/2015-Present
**Associate Professor in Statistics***School of Mathematical Sciences, University of Nottingham, UK.*- 09/2008-08/2015
**Lecturer/Assistant Professor in Statistics***School of Mathematical Sciences, University of Nottingham, UK.*- 09/2006-08/2008
**Research Fellow***School of Mathematical Sciences, University of Nottingham, UK.*

- 09/2006-04/2012
**Postgraduate Certificate in Higher Educations***University of Nottingham, UK.*- 09/2003-09/2006
**PhD in Statistics***Department of Mathematics, Lancaster University.**Supervisor: Prof Gareth Roberts, Examiners: Prof Jonathan Tawn, Stephen G. Walker**[Funded by a Faculty Scholarship from Lancaster University and EPSRC]*- 09/2002-09/2003
**MSc in Medical Statistics (With distinction)***Department of Mathematics, Lancaster University.**Dissertation Supervisor: Prof Leo Held**[Funded by an NHS Scholarship]*- 09/1998-09/2002
**BSc in Statistics***Department of Statistics, Athens University of Economic and Business.**Grade: 8.64/10 (Equivalent to a First)*

*Submitted*- Alharthi, M. Kypraios, T., O'Neill, P.D. (2017) Bayes factors for partially observed stochastic epidemic models. [arXiv]

*To Appear*- 2017
Iqbal M, Doherty N, Page AML, Qazi SNA, Ajmera I, Lund PA, et al. (2017) Reconstructing promoter activity from Lux bioluminescent reporters.

*PLoS Computational Biology*13(9): e1005731. [final-version]Prangle, D., Everitt, R.G., Kypraios, T. (2017) A rare event approach to high dimensional Approximate Bayesian computation.

*Statistics and Computing*. To Appear. doi:10.1007/s11222-017-9764-4 [final-version]Kypraios, T., O'Neill, P.D. (2017) Bayesian nonparametrics for stochastic epidemic models.

*Statistical Science*. [final-version]Kypraios, T., Neal, P., Prangle D. (2017) A tutorial introduction to Bayesian inference for stochastic epidemic models using Approximate Bayesian Computation.

*Mathematical Biosciences*287:42-53. [final-version]Stockdale, J.E, Kypraios, T. O'Neill P.D. (2017) Modelling and Bayesian analysis of the Abakaliki Smallpox Data.

*Epidemics*. [final-version] doi:10.1016/j.epidem.2016.11.005Boehm-Strm, P., Füchtemeier M., Foddis M., Mueller, S., Trueman, R. C., Zille, M., Rinnenthal, JL, Kypraios, T., Shaw, L., Dirnagl, U., Farr, T.D. (2017) Neuroimaging Biomarkers Predict Brain Structural Connectivity Change in a Mouse Model of Vascular Cognitive Impairment.

*Stroke*, [final-version] doi.org/10.1161/STROKEAHA.116.014394

- 2016
Papanikolaou, N.E. , Williams, H., Demiris, N. Preston, S.P., Milonas, P.G, Kypraios, T. (2016) Bayesian Inference and Model Choice for Holling's Disc Equation: An Application to

*Aphidophagous*ladybirds.*Community Ecology*, 17(1): 71-78. doi: 10.1556/168.2016.17.1.9Acharya, A., Kypraios, T., Guta, M. (2016) Statistically efficient tomography of low rank states with incomplete measurements.

*New Journal of Physics*, 18:043018. [arXiv]Fallaize, C.J. and Kypraios, T. (2016) Exact Bayesian Inference for the Bingham Distribution.

*Statistics and Computing*. 26(1-2):349-360. doi:10.1007/s11222-014-9508-7Gerstgrasser, M., Nicholls, S., Stout, M., Smart, K., Kypraios, T., Powell, C., Stekel D. (2016). A Bayesian approach to analyzing phenotype microarray data enables estimation of microbial growth parameters.

*Journal of Bioinformatics and Computational Biology*14 (3):1650007. http://dx.doi.org/10.1142/S021972001650007Worby, C.J., O'Neill P.D., Kypraios, T., Robotham, J.V., De Angelis, D., Cartwright, E.J.P, Peacock, S.J, Cooper, B.S. (2016). Reconstructing transmission networks for communicable diseases using densely sampled genomic data: a generalized approach.

*Annals of Applied Statistics*, 10 (1): 395–417.Wei, Y., Kypraios, T., O'Neill, P.D., Huang, S.S., Rifas-Shiman, S.L., and Cooper, B.S. (2016) Modelling Transmission of Vancomycin-Resistant Enterococci in Intensive Care Units.

*Statistical Methods in Medical Research*, doi:10.1177/0962280215627299. [arXiv]Xu, X., Kypraios, T. and O'Neill, P.D. (2016) Bayesian nonparametric inference for stochastic epidemic models using Gaussian Processes.

*Biostatistics*, 17(4):619-633. [final-version]Auguet, O.T., Betley, J.R., Stabler, R.A., Patel, A., Ioannou, A., Marbach, H., Hern, P., Aryee, A., Desai, N., Karadag, T., Grundy, C., Gaunt, M., Cooper, B.S., Edgeworth, J.D., Kypraios, T. (2015) Evidence for Community Transmission of Community-Associated but not Healthcare-Associated Methicillin-Resistant Staphylococcus Aureus Strains Linked to Social and Material Deprivation.

*PLoS Medicine*, 13(1): e1001944.Verykouki, E., Kypraios T., O'Neill P.D. (2016). Modelling the effect of antimicrobial treatment on carriage of hospital pathogens with application to MRSA.

*Biostatistics*, 17 (1):65-78.Papanikolaou, N.E. Demiris, N., Milonas, P.G., Preston, S.P., Kypraios, T. (2016) Does mutual interference affect the feeding rate of

*aphidophagous coccinellids*? A modelling perspective.*PloS ONE*, 11 (1): e0146168.

- 2015
Butucea, C. Guta, M., Kypraios, T. (2015) Spectral thresholding quantum tomography for low rank states.

*New Journal of Physics*, 17:113050. [arXiv]White, S., Kypraios, T., and Preston S. (2015) Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution.

*Statistics and Computing*, 25(2):289–301.Neal, P., and Kypraios, T. (2015). Exact Bayesian inference via data augmentation.

*Statistics and Computing*, 25(2):333-347.

- 2014
Catana, C., Kypraios, T. and Guta, M. (2014) Maximum likelihood versus likelihood-free quantum system identification in the atom maser.

*J. Phys. A: Math. Theor.*47 (41):415302.Ellis, M., Pezaros, D.P., Kypraios T., Perkins, C. (2014) A two-level Markov model for packet loss in UDP/IP-based real-time video applications targeting residential users.

*Computer Networks*, 70:384-399.Demiris N., Kypraios, T., Smith V. (2014) On the Epidemic of Financial Crises.

*Royal Statistical Society: Series A (Statistics in Society)*, 177: 697-723.Knock, E. Kypraios, T., Morgan, P. and Sotiropoulos, S. (2014). Noise Model Selection for Multichannel Diffusion-weighted MRI. In

*The Contribution of Young Researchers to Bayesian Statistics, Springer Proceedings in Mathematics & Statistics*(63):149-153

- 2013
Worby C., Jeyaratnam D., Robotham J.V. , Kypraios T., O'Neill P.D., De Angelis D., French G., and Cooper, B.S. (2013) Estimating the effectiveness of isolation and decolonisation measures in reducing MRSA transmission in hospital general wards:a model-based analysis.

*American Journal of Epidemiology*. 177(11):1306-1313.Vlek A.L., Cooper B.S., Kypraios T., Cox A., Edgeworth J.D., and Auguet O.T. (2013). Clustering of Antimicrobial Resistance Outbreaks Across Bacterial Species in the Intensive Care Unit.

*Clinical Infectious Diseases*, 57(1):65-76.Fontana, A. Copetti, M., Mazzoccoli, G., Kypraios, T, and Pellegrini, F. (2013). A linear mixed model approach to compare the evolution of multiple biological rhythms.

*Statistic in Medicine*, 32(7):1125-1135.

- 2012
Guta, M. Kypraios, T. and Dryden, I. (2012) Rank-based model selection for multiple ions quantum tomography.

*New Journal of Physics*, 14:e105002.Ellis, M., Pezaros, D., Kypraios, T. and Perkins, C. (2012) Modelling Packet Loss in RTP-based Streaming Video for Residential Users.

*Proceedings of the 37th IEEE Conference on Local Computer Networks, Clearwater, FL, USA*.Cooper, B.S., Kypraios, T., Batra R., Wyncoll, D., Tosas, O., Edgeworth, J.D. (2012) Quantifying type-specific reproduction numbers for nosocomial pathogens: evidence for heightened transmission of an Asian sequence type 239 MRSA clone.

*Plos Computational Biology*, 8(4): e1002454.Katsounaros, I., Dortitsou, M., Polatides, C., Preston, S., Kypraios, T., Kyriacou, G. (2012). Reaction pathways in the electrochemical reduction of nitrate on tin.

*Electrochemica Acta*, 71:270-276.Miller, C.E., Batra, R., Patel, A.K., Klein, J., Otter, J., Cooper, B.S., Kypraios, T., Tosas, O., Edgeworth, J.D. (2012)$ An association between bacterial genotype combined with a high vancomycin MIC and risk of endocarditis in methicillin-resistant Staphylococcus aureus blood stream infection.

*Clinical Infectious Diseases*54(5):591-600.

- 2011
Kypraios T., O'Neill P.D., Jones, D., Ware J., Edgeworth J.D. , Cooper B.S. (2011) Effect of systemic antibiotics and topical chlorhexidine on methicillin-resistant Staphylococcus aureus (MRSA) carriage in intensive care unit patients.

*Journal of Hospital Infections*, 79(3):222-226.Britton, T., Kypraios T., O'Neill P.D. (2011) Inference for Epidemics with Three Levels of Mixing: Methodology and Application to a Measles Outbreak.

*Scandinavian Journal of Statistics*, 38(3):578-599.

- 2010
Kypraios T., O'Neill P.D., Huang S., Rifas-Shiman, S.L., Cooper B.S. (2010) Assessing the role of undetected colonization and isolation precautions in reducing Methicillin-Resistant Staphylococcus aureus transmission in intensive care units

*BMC Infectious Diseases*, 10:29.Sotiropoulos, S.N., Jones D.E., Bai, L., Kypraios T. (2010) Exact and analytic Bayesian inference for orientation distribution functions.

*2010 IEEE International Symposium on Biomedical Imaging From Nano to Macro*, (2)3:1189-1192.

- 2009
Kypraios, T. (2009). A note on maximum likelihood estimation of the number of initial number of susceptibles in the General Stochastic Epidemic model.

*Statistics and Probability and Letters*, (79)18:1972-1976.Jewell C.P., Kypraios T., Neal P., Roberts, G.O. (2009) Bayesian Analysis of Emerging Infectious Diseases.

*Bayesian Analysis*, (4)2:191-222.

- 2008
- Jewell C.P., Kypraios T., Christley, R., Roberts, G.O (2008). A Novel Approach to Real-Time Risk-Prediction for Emerging Infectious Diseases: A Case Study in Avian Influenza H5N1.
*Preventive Veterinary Medicine Journal*, (79)1:19-28

- Jewell C.P., Kypraios T., Christley, R., Roberts, G.O (2008). A Novel Approach to Real-Time Risk-Prediction for Emerging Infectious Diseases: A Case Study in Avian Influenza H5N1.
- 2007
- Kypraios T. (2007) Efficient Bayesian Inference for Partially Observed Stochastic Epidemics and A New Class of Semi-Parametric Time Series Models.
*PhD thesis*.

- Kypraios T. (2007) Efficient Bayesian Inference for Partially Observed Stochastic Epidemics and A New Class of Semi-Parametric Time Series Models.

- 05/2016-02/2020
NERC (Co-I, PI: Dr Dov Stekel)

*EVAL-FARMS: Evaluating the Threat of Antimicrobial Resistance in Agricultural Manures and Slurries*; [£1,500,000]- 06/2016-08/2016
UoN Data Driven Discovery Summer Internship

*Statistical Analysis of Twitter Data*; [£2,000]- 03/2016-06/2016
UoN Discipline Bridging Award (Co-PI, other PI: Dr Tracy Farr)

*Structural and functional connectivity changes to predict cognitive decline in a model of vascular cognitive impairment*; [£5,000].- 11/2012-11/2015
BBSRC (Co-I, PI: Dr Dov Stekel)

*High throughput analysis of cell growth data from phenotype arrays'*; [£273,083].- 10/2012-09/2014
EPSRC (PI):

*Bayesian Nonparametric Inference for Stochastic Epidemic Models*; [£96,432].- 09/2012-10/2013
Royal Society Research Equipment Grant (PI):

*Novel Statistical Methods for Imaging Brain Tissue Structure*; [£9,600].- 09/2012-04/2013
EPSRC Small Equipment Grant (PI):

*Monte Carlo Methods for Large-Scale Inference*; [£8,500].- 06/2013-08/2013
Wellome Trust Undergraduate Summer Bursary (PI):

*Modelling Brain Connectivity*, [£1,440].- 06/2013-08/2013
London Mathematical Society Undergraduate Summer Bursary (PI):

*Statistical methods for characterizing quantum devices*; [£1,440].- 01/2012-04/2012
EPSRC Research Development Fund (Co-PI):

*Advanced statistical Methods for Quantum Engineering*; [£4,800].- 08/2011-12/2012
University of Nottingham Early Career Research and Knowledge Transfer Award (PI):

*Modelling Brain Connectivity within a Bayesian framework using DW--MRI data*; [£23,858].- 01/2012-04/2012
EPSRC Research Development Fund (CoPI):

*Monte carlo estimation of parameters for large biological data sets using graphical processing units*; [£ 8,904].- 07/2011-08/2011
Nuffield Foundation Undergraduate Bursary (PI):

*Parameter Identification for Differential Equation Models*[£1,440].- 01/2011-01/2013
Pfizer Anti-Infectives Research Foundation (Co-I, PI: Dr Jonathan Edgeworth):

*Modelling Antimicrobial Use and and Transmission of Resistance in ICUs*[£60,020].- 07/2010-12/2010
London Mathematical Society Research Grant (PI):

*Modelling Internet Traffic Using Latent Branching Trees*; [£480].- 09/2009-01/2010
EPSRC Bridging the Gaps pump-prime funding (CoI):

*Exploring potential for novel methods of parametric inference for stochastic chemical kinetic models and applications in systems and synthetic biology*; [£10,000].- 08/2009-08/2009
Hospital Infection Society Travel Grant; [£350].

- 06/2009-09/2009
EPSRC Bridging the Gaps pump-prime funding (PI):

*Bayesian Inference for Diffusion-weighted Magnetic Resonance Images*; [£3,000].- 05/2008-11/2008
EPSRC Bridging the Gaps award (PI):

*A GIS approach to model the 2001 Foot and Mouth outbreak*; [£2,900].

- 2017
Invited Seminar at Loughborough University.

Invited speaker at the

*Probability in North-East meeting*at the University of Leeds.Invited seminar at the School of Mathematics and Statistics at the University of Sheffield.

- 2016
Keynote speaker at the 52nd Gregynog Statistical Conference.

Invited seminar at the Department of Mathematics and Statistics at the University of Newcastle.

- 2015
Invited guest lecture on Bayesian Statistics at Cranfield University.

Contributed talk at the

*9th Workshop on Bayesian Inference in Stochastic Processes*in Istanbul.Invited talk at the

*Workshop in High-dimensional problems and quantum physics*in Paris.Invited seminar at the Department of Engineering at the University of Cambridge.

- 2014
Invited seminar at the

*Mathematical Challenges for Long Epidemic Time Series*workshop at Warwick University.Invited seminar at Lancaster University.

- 2013
Invited talk at the

*6th International Conference in Computational and Methodological Statistics*, London.Invited talk at the

*Design and Analysis of Infectious Disease Studies*workshop which took place at Mathematisches Forschungsinstitut Oberwolfach.Invited talk at the

*Swiss Meeting for Infectious Disease Dynamics*, ETH, Zurich, Switzerland.Invited talk at the

*From Spectral to Particle Filters*workshop in the University of Reading.Invited talk at the

*AMS Joint Statistical Meeting in Montreal*in Canada.- 2012
Invited seminar at the University of Bath.

Invited seminar at Cranfield University.

Invited talk at the

*New Directions in Quantum Statistics*conference in Nottingham.Invited talk at the

*Workshop on Mathematical Modelling of Antibiotic Resistance (WARM)*in Paris.- 2011
Invited talk at a Royal Statistical Society General Application Section meeting.

Invited talk at the

*Inference For Epidemic-related Risk conference*in Warwick.Invited seminar at the School of Mathematics in the University of Birmingham.

Invited talk at the ICMS workshop on

*Networks: Stochastic Models for Populations and Epidemics*in Edinburgh.Invited talk at the

*ABC Day*workshop in the London School of Hygiene and Tropical Medicine.- 2010
Contributed talk at the

*Statistical modelling and inference for networks*workshop in Bristol.Invited seminar at the London School of Hygiene and Tropical Medicine.

Invited seminar at the Royal Statistical Society Manchester Local Group.

Invited seminar at the Inference Group in the Department of Computing Science at the University of Glasgow.

Invited seminar at the School of Mathematical and Computer Sciences at Heriot-Watt University.

Invited seminar at the National Institute Health Research seminar series at the Department of Statistics at the University of Warwick.

Invited seminar at the Department of Statistics, University of Warwick.

Invited seminar at the Cambridge Infectious Diseases Consortium.

- 2009
Invited talk at the

*Design and Analysis of Infectious Disease Studies*workshop which took place at Mathematisches Forschungsinstitut Oberwolfach.Invited talk at the

*EPSRC Symposium Workshop on Markov Chain-Monte Carlo*held at the University of Warwick.Invited seminar at the Department of Statistics, London School of Economics.

- 2008
Invited seminar at the School of Mathematical Sciences at the University of Newcastle.

Invited talk at a

*Spatio-temporal and Network Modelling of Diseases*workshop in Tubingen, Germany.Invited talk at the

*2008 Royal Statistical Society Conference*.Invited briefing at the Health Protection Agency to the UK Government Chief Scientific Adviser.

Invited seminar at the Pasteur Institute in Paris.

- 2007
Contributed talk at the

*Health Protection Conference*held at the University of Warwick.- 2006
Invited talk at the Isaac Newton institute workshop on

*Stochastic Computation for the Analysis of Ecological and Epidemiological Data*in Cambridge.- 2005
Invited talk at the

*3rd Young Researchers Day*at Louvain-la-Neuve University, Belgium.Invited seminar at University Center for Statistics at the Katholieke Universiteit Leuven, Belgium.

*Post Doctoral Research Associates/Fellows*

- 11/2012-08/2015
Dr Mike Stout @ University of Nottingham (jointly with D.J. Stekel; Funded by BBSRC.)

- 10/2012-10/2013
Dr Edward Knock @ University of Nottingham.

- 01/2012-06/2012
Dr Edward Knock @ University of Nottingham.

- 09/2012-12/2012
Simon White @ University of Nottingham; jointly with S.P. Preston.

*PhD Graduates*

- 2016
Lisa Mott. University of Nottingham; jointly with C.J. Brignell.

Muteb Alharthi, University of Nottingham; jointly with P.D. O'Neill.

- 2015
Kamonrat Supwahan. University of Nottingham; jointly with R.D. Willkinson.

Xiaoguang Xu.University of Nottingham; jointly with P.D. O'Neill.

- 2013
Colin Worby. University of Nottingham; jointly with P.D. O'Neill.

Eleni Verykouki. University of Nottingham; jointly with P.D. O'Neill.

*PhD Supervision*

- 09/2016-Present
George Aristotelous @ University of Nottingham; jointly with P.D. O'Neill

- 09/2016-Present
Rowland, Seymour @ University of Nottingham; jointly with P.D. O'Neill.

- 09/2014-Present
Anirudh Acharya @ University of Nottingham; jointly with M. Guta.

- 09/2014-Present
Jessica Stockdale @ University of Nottingham; jointly with P.D. O'Neill.

- 09/2013-Present
Matthew Levitt @ University of Nottingham; jointly with M. Guta.

- 09/2013-Present
Rosanna Cassidy @ University of Nottingham; jointly with P.D. O'Neill.

*Undergraduate Supervision*

- 07/2016-09/2016
Alexander Lewis @ University of Nottingham (funded by UON)

- 06/2013-08/2013
Elizabeth Ho @ University of Nottingham (funded by Wellcome Trust).

- 06/2013-08/2013
Samuel Shleton @ University of Nottingham (funded by LMS and jointly with M. Guta).

- 06/2011-08/2011
Hannah Williams @ University of Nottingham; jointly with S.P. Preston.

- 06/2009-09/2009
David Jones @ University of Nottingham.

- 06/2008-09/2008
David Jones @ University of Nottingham.

- 06/2008-08/2008
Jennifer Ware @ University of Nottingham jointly with P.D. O'Neill).

- 06/2007-08/2007
Jonathan Algar @ University of Nottingham; jointly with P.D. O'Neill).

- 2010-2016
Summer Institute in Statistics and Modeling in Infectious Diseases @ University of Washington, Seattle.

- 2016-2017
G12SMM: Statistical Models and Methods @ the University of Nottingham.

- 2016-2017
G14FOS: Fundamentals of Statistics @ University of Nottingham. G14STF: Statistical Foundations @ University of Nottingham.

- 2015-2016
G12SMM: Statistical Models and Methods @ the University of Nottingham.

- 2015-2016
G14FOS: Fundamentals of Statistics @ University of Nottingham. G14STF: Statistical Foundations @ University of Nottingham.

- 2014-2015
G12SMM: Statistical Models and Methods @ the University of Nottingham.

- 2014-2015
G14FOS: Fundamentals of Statistics @ University of Nottingham.

- 2013-2014
G12SMM: Statistical Models and Methods @ the University of Nottingham.

- 2013-2014
G14TFG: Times Series and Forecasting @ the University of Nottingham.

- 2012-2013
G12SMM: Statistical Models and Methods @ the University of Nottingham.

- 2012-2013
HG2MPN: Probab. and Numer. Techniques for Engineers @ the University of Nottingham.

- 2011-2012
G12SMM: Statistical Models and Methods @ the University of Nottingham.

- 2011-2012
G14TFG: Times Series and Forecasting @ the University of Nottingham.

- 2010-2011
G14FOS: Fundamentals of Statistics @ University of Nottingham.

- 2010-2011
G14TFG: Times Series and Forecasting @ the University of Nottingham.

- 2009-2010
G14FOS: Fundamentals of Statistics @ University of Nottingham.

- 2009-2010
G14TFG: Times Series and Forecasting @ the University of Nottingham.

- 2008-2009
G14FOS: Fundamentals of Statistics @ University of Nottingham.

- 2008-2009
G14TFG: Times Series and Forecasting @ the University of Nottingham.

- 2016-Present
Director of Resources, School of Mathematical Sciences, University of Nottingham.

- 2014-Present
Chair of the Royal Statistical Society East Midlands Local Group.

- 2014-Present
Member of the Royal Statistical Society Statistical Computing Section.

- 2014-Present
Associate Editor, Journal of Mathematical Biosciences, Elsevier.

- 2014-Present
Web Liaison Officer, School of Mathematical Sciences, University of Nottingham.

- 2013-Present
Associate Editor, Statistics and Computing, Springer.

- 2011-2014
Director of International Affairs, School of Mathematical Sciences, University of Nottingham.

- 2008-2011
Internal and external departmental Probability and Statistics seminar organizer, School of Mathematical Sciences, University of Nottingham.

- Refereeing
*Biometrika, Journal of American Statistical Association, Biostatistics, Annals of Applied Statistics, Statistics and Computing, Journal of Royal Statistical Society Series C, Plos One, IEEE Special Issue on Networks, Biometrics, Journal of Statistical Planning and Inference, Biometrical journal, AISTATS 2012, 2013 and 2014, Spatial and Spatio-temporal Epidemiology, Methods and Algorithms for Scientific Computing section of SISC*.- Memberships
Fellow of Royal Statistical Society

Junior Member of the Isaac Newton Institute for Mathematical Sciences.

• +44 (0)7804 227889 • http://www.maths.nottingham.ac.uk/~tk/