Education Aims
To provide understanding in the use and development of computer models to simulate neuronal behaviour from the level of the single neuron to that of neuronal networks.
Education AimsTo provide understanding in the use and development of computer models to simulate neuronal behaviour from the level of the single neuron to that of neuronal networks. |
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Learning OutcomesTo demonstrate and use computer models to investigate and simulate properties of neuronal behaviour from the level of the single neuron to that of neuronal networks |
Students are strongly encouraged to download the software modelling package NEURON that will be used throughout this course. This is free, multi-platform, and has extensive supporting documentation and tutorials. Workshops will make extensive use of the tutorial and simulations package Neurons in Action (available in computer lab C77 and all University Campus Library PCs).
Will it ever happen that mathematicians will know enough of the subject of the physiology of the brain and that neurologists know enough of mathematical discovery for efficient cooperation to be possible?
-- Jacques Hadamard from his 1945 book The Psychology of Invention in the Mathematical Field.
| Contents | |
| CNN 1 | Module overview & assessment |
| CNN 2A | Neurobiology & Computational Sciences (extra lecture material) |
| CNN 2B | Why use models? (extra lecture material) |
| CNN 3A | Channels: Neurons-in-Action 2 - Tutorials |
| CNN 3B | Hodgkin-Huxley model: Neurons-in-Action 2 - The Na Action Potential (extra lecture material) |
| CNN 4 | Synapses: Neurons-in-Action - Neuromuscular junction (ACh), Postsynaptic inhibition (GABA), Synaptic integration. My First NEURON Tutorial |
| CNN 5 | NEURON: Channel and Cell Builder (extra lecture material for dendritic modelling). NIA2: Axons. Cell Builder Tutorial. IT session file. |
| CNN 6 | NEURON: Network Builder (extra lecture material) Network Builder Tutorial Action potential session file. Half Center session file. |
| CNN 7 | Poster questions and potential poster projects. |
| CNN 8 | Questions & Problems 1 |
| CNN 9 | Draft poster due |
| CNN 10 | Questions & Problems 2 |
| CNN | Poster electronic hand-in deadline 10:00am 3 May to Rob.Mason@nottingham.ac.uk |
| CNN 11 | Poster Assessment Session 11 May 9am (E1) |
| Neurons in action: tutorials and simulations using NEURON (ver. 2.0), John W. Moore and Ann E. Stuart, Sinauer, 2007. |
| The NEURON Book, Nicholas T. Carnevale, Michael L. Hines, Cambridge University Press, 2006. |
| Spikes, Decisions, and Actions: The Dynamical Foundations of Neuroscience, Wilson, H., Oxford University Press, 1999. |
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Neurons in Action is a tutorial and simulations package using NEURON.
NEURON is a simulation environment for modeling individual neurons and networks of neurons.
ModelDB is an archive of published models that are ready to run!
NeuroMorpho.Org is a centrally curated inventory of digitally reconstructed neurons.
Computational Neuroscience on the World Wide Web. An index for computational neurobiology.
Encyclopedia of Computational Neuroscience. A peer-reviewed Wiki.
stephen.coombes@nottingham.ac.uk