MathsNet: Research Student Directory

Name Forrester, Michael Joseph
Group Mathematical Medicine and Biology
Room A14, Maths
Telephone +44 (0) 115 [direct dial]
Thesis Title Synchronisation and propagation in human cortical networks
Thesis Abstract The idea of modelling the brain as a complex network is now well established. However, the emergence of pathological brain states via the interaction of large interconnected neuronal populations remains poorly understood. For instance, current theoretical study of epileptic seizures is flawed by dynamical simulation on inadequate network models, and by the absence of customised network measures that capture pathological connectivity patterns. This project aims to address these deficiencies via improved computational models with which to investigate thoroughly the influence of the geometry and connectivity of the human brain on irregular behaviour, and the development of novel network measures with which to characterise diseased brains. Such investigations will be informed by exhaustive patient datasets (such as recordings of neural activity in epilepsy patients and age-matched controls), and will be used to study strategies to diagnose and treat pathological brain conditions.
School contact information School of Mathematical Sciences
University of Nottingham
University Park
Nottingham, NG7 2RD
Tel: +44 (0) 115 951 4949
Fax: +44 (0) 115 951 4951